BDBM50111710 5-Bromo-N-hydroxy-2-{[4-(4-hydroxy-but-2-ynyloxy)-benzenesulfonyl]-methyl-amino}-3-methyl-benzamide::CHEMBL18943

SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1

InChI Key InChIKey=ZEZNNQDUSMNIDE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50111710   

LigandPNGBDBM50111710(5-Bromo-N-hydroxy-2-{[4-(4-hydroxy-but-2-ynyloxy)-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111710(5-Bromo-N-hydroxy-2-{[4-(4-hydroxy-but-2-ynyloxy)-...)
Affinity DataIC50: 83nMAssay Description:Inhibition of Matrix metalloprotease-13 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111710(5-Bromo-N-hydroxy-2-{[4-(4-hydroxy-but-2-ynyloxy)-...)
Affinity DataIC50: 477nMAssay Description:Inhibition of Matrix metalloprotease-9 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111710(5-Bromo-N-hydroxy-2-{[4-(4-hydroxy-but-2-ynyloxy)-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed