BDBM50111711 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(3-phenyl-prop-2-ynyloxy)-benzenesulfonyl]-amino}-benzamide::CHEMBL418737

SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OCC#Cc2ccccc2)cc1

InChI Key InChIKey=PTUSTBHDXAVNPJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50111711   

LigandPNGBDBM50111711(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(3-phenyl-...)
Affinity DataIC50: 66nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111711(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(3-phenyl-...)
Affinity DataIC50: 321nMAssay Description:Inhibition of Matrix metalloprotease-13 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111711(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(3-phenyl-...)
Affinity DataIC50: 857nMAssay Description:Inhibition of Matrix metalloprotease-9 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50111711(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(3-phenyl-...)
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed