BDBM50111719 CHEMBL19037::N-(4-Aminomethyl-thiazol-2-ylmethyl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide

SMILES Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1nc(CN)cs1

InChI Key InChIKey=WYQRAGPLMGNLNP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111719   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111719(N-(4-Aminomethyl-thiazol-2-ylmethyl)-2-(6-methyl-2...)
Affinity DataKi:  136nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111719(N-(4-Aminomethyl-thiazol-2-ylmethyl)-2-(6-methyl-2...)
Affinity DataKi: >168nMAssay Description:In vitro inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111719(N-(4-Aminomethyl-thiazol-2-ylmethyl)-2-(6-methyl-2...)
Affinity DataKi: >338nMAssay Description:In vitro inhibitory constant against factor Xa (FXa) was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed