BDBM50111996 CHEMBL173382::N-[2-(5-Chloro-1H-indol-3-yl)-ethyl]-N'-hydroxy-oxalamide

SMILES ONC(=O)C(=O)NCCc1c[nH]c2ccc(Cl)cc12

InChI Key InChIKey=HCKYIMJMJTUVAP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111996   

TargetMatrix metalloproteinase-9(Human)
University of Bielefeld

Curated by ChEMBL
LigandPNGBDBM50111996(N-[2-(5-Chloro-1H-indol-3-yl)-ethyl]-N'-hydroxy-ox...)
Affinity DataKi:  350nMAssay Description:Inhibitory activity against human gelatinase B (matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Bielefeld

Curated by ChEMBL
LigandPNGBDBM50111996(N-[2-(5-Chloro-1H-indol-3-yl)-ethyl]-N'-hydroxy-ox...)
Affinity DataKi:  1.40E+4nMAssay Description:Tested for its inhibitory activity against neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Bielefeld

Curated by ChEMBL
LigandPNGBDBM50111996(N-[2-(5-Chloro-1H-indol-3-yl)-ethyl]-N'-hydroxy-ox...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of membrane type MT1-MMP (Matrix metalloprotease-14)catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed