BDBM50112177 CHEMBL3608433

SMILES COc1nn(cc1Nc1nc(nc2n(cnc12)C(C)C)N1C[C@@H](F)[C@@H](C1)NC(=O)C=C)C1CCN(C)C1

InChI Key InChIKey=BSFRRHNDBNCWNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112177   

TargetEpidermal growth factor receptor(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50112177(CHEMBL3608433)
Affinity DataIC50: 142nMAssay Description:Inhibition of wild type EGFR in human A549 cells assessed as inhibition of phosphorylation at Y1068 after 2 hrs by sandwich ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed