BDBM50112233 3-(4-Methoxy-phenyl)-1-methyl-5-(4-methyl-thiazol-2-yl)-1H-[2,4']bipyridinyl-6-one::CHEMBL294600
SMILES COc1ccc(cc1)-c1cc(-c2nc(C)cs2)c(=O)n(C)c1-c1ccncc1
InChI Key InChIKey=XNIDSAVZEZPOBT-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50112233
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Binding affinity by displacement of [3H]-Ro-15-1788 from recombinant human gamma-aminobutyric-acid A receptor alpha3,beta3,gamma2 stably expressed in...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 8.60nMAssay Description:Displacement of [3H]-Ro-15-1788 from human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 stably expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of [3H]-Ro-15-1788 binding to human GABA A receptor (alpha1-beta3-gamma2) stably expressed in L(tk-) cells.More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Displacement of [3H]-Ro-15-1788 from human GABA-A receptor alpha5-beta3-gamma2 subunits expressed in L(tk-) cellsMore data for this Ligand-Target Pair