BDBM50112296 4-Iodo-benzoic acid 9-(3,4-dichloro-benzylidene)-7-aza-tricyclo[4.3.1.0*3,7*]dec-2-ylmethyl ester::CHEMBL299019

SMILES Clc1ccc(\C=C2/CN3C4CCC3C(COC(=O)c3ccc(I)cc3)C2C4)cc1Cl

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112296   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112296(4-Iodo-benzoic acid 9-(3,4-dichloro-benzylidene)-7...)
Affinity DataKi:  48.7nMAssay Description:Inhibition of high affinity re-uptake of [3H]5-HT (serotonin) into nerve ending synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112296(4-Iodo-benzoic acid 9-(3,4-dichloro-benzylidene)-7...)
Affinity DataKi:  8.59E+3nMAssay Description:Ability to inhibit high affinity reuptake of [3H]-NE (Norepinephrine transporter) into nerve ending synaptosomes prepared from brain regionsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50112296(4-Iodo-benzoic acid 9-(3,4-dichloro-benzylidene)-7...)
Affinity DataKi:  1.77E+4nMAssay Description:Ability to inhibit high affinity reuptake of [3H]DA from dopamine transporter into nerve endings synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed