BDBM50112515 4'-{2-Ethyl-5-[1-(1-imino-ethyl)-piperidin-4-yloxy]-benzoimidazol-1-ylmethyl}-biphenyl-4-carboxamidine::CHEMBL25063

SMILES CCc1nc2cc(OC3CCN(CC3)C(C)=N)ccc2n1Cc1ccc(cc1)-c1ccc(cc1)C(N)=N

InChI Key InChIKey=KCQIXXZEEFUYGH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112515   

TargetSerine protease 1(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112515(4'-{2-Ethyl-5-[1-(1-imino-ethyl)-piperidin-4-yloxy...)
Affinity DataKi:  150nMAssay Description:Tested in vitro for the selectivity against trypsin (Trp)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112515(4'-{2-Ethyl-5-[1-(1-imino-ethyl)-piperidin-4-yloxy...)
Affinity DataKi:  670nMAssay Description:Tested in vitro for the inhibitory potency against Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112515(4'-{2-Ethyl-5-[1-(1-imino-ethyl)-piperidin-4-yloxy...)
Affinity DataKi:  1.50E+3nMAssay Description:Tested in vitro for the selectivity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed