BDBM50112542 2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-((S)-1-hydroxymethyl-2-methyl-propyl)-acetamide::2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(1-hydroxymethyl-2-methyl-propyl)-acetamide::CHEMBL25030

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N[C@H](CO)C(C)C)c2c1

InChI Key InChIKey=WDFPKHUPZPMAJW-OAQYLSRUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112542   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112542(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112542(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against ovine Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50112542(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  370nMAssay Description:Inhibitory concentration against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50112542(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  370nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed