BDBM50112651 4-[(6-Chloro-2H-chromene-3-carbonyl)-amino]-5-(2-oxo-pyrrolidin-3-yl)-pent-2-enoic acid ethyl ester::4S-[(6-Chloro-2H-chromene-3-carbonyl)amino]-5-(2-oxopyrrolidin-3S-yl)pent-2-enoic Acid Ethyl Ester::CHEMBL293441

SMILES CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)C1=Cc2cc(Cl)ccc2OC1

InChI Key InChIKey=FUDPGCHBEDGBSA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112651   

TargetGenome polyprotein(Human rhinovirus B)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50112651(4-[(6-Chloro-2H-chromene-3-carbonyl)-amino]-5-(2-o...)
Affinity DataEC50:  160nMAssay Description:Inhibition of Human Rhinovirus 14 (HRV14) Protease 3CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50112651(4-[(6-Chloro-2H-chromene-3-carbonyl)-amino]-5-(2-o...)
Affinity DataEC50:  460nMAssay Description:50% effective concentration required to inhibit Human Rhinovirus 10 Protease 3CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50112651(4-[(6-Chloro-2H-chromene-3-carbonyl)-amino]-5-(2-o...)
Affinity DataEC50:  650nMAssay Description:50% effective concentration required to inhibit Human Rhinovirus 2 Protease 3CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50112651(4-[(6-Chloro-2H-chromene-3-carbonyl)-amino]-5-(2-o...)
Affinity DataEC50:  5.10E+3nMAssay Description:50% effective concentration required to inhibit Human Rhinovirus 1A Protease 3CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed