BDBM50112690 2,4-Bis-benzo[1,3]dioxol-5-yl-6-isopropoxy-2H-chromene-3-carboxylic acid::CHEMBL416675

SMILES CC(C)Oc1ccc2OC(C(C(O)=O)=C(c3ccc4OCOc4c3)c2c1)c1ccc2OCOc2c1

InChI Key InChIKey=MNDFDHZJDKQKOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112690   

TargetEndothelin-1 receptor(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112690(2,4-Bis-benzo[1,3]dioxol-5-yl-6-isopropoxy-2H-chro...)
Affinity DataIC50: 3.20nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]ET1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112690(2,4-Bis-benzo[1,3]dioxol-5-yl-6-isopropoxy-2H-chro...)
Affinity DataIC50: 170nMAssay Description:Binding affinity to endothelin B receptor measured by inhibition of [125I]ET-3 binding recombinant pig ET-B receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed