BDBM50112715 CHEMBL62578::N-[2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-methoxy-phenyl)-2H-chromene-3-carbonyl]-methanesulfonamide

SMILES COc1ccc(cc1)C1=C(C(Oc2ccc(OC(C)C)cc12)c1ccc2OCOc2c1)C(=O)NS(C)(=O)=O

InChI Key InChIKey=NYXQPDDLPFOZLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112715   

TargetEndothelin-1 receptor(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112715(N-[2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-metho...)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]ET1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed