BDBM50112833 CHEMBL280587::N-(1-Benzyl-2-carbamoyl-2-oxo-ethyl)-2-(2-naphthalen-2-yl-vinyl)-benzamide

SMILES NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1ccccc1C=Cc1ccc2ccccc2c1

InChI Key InChIKey=PMFBLJXNSAHZSG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112833   

TargetCalpain-1 catalytic subunit(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50112833(N-(1-Benzyl-2-carbamoyl-2-oxo-ethyl)-2-(2-naphthal...)
Affinity DataKi:  6nMAssay Description:Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50112833(N-(1-Benzyl-2-carbamoyl-2-oxo-ethyl)-2-(2-naphthal...)
Affinity DataKi:  99nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50112833(N-(1-Benzyl-2-carbamoyl-2-oxo-ethyl)-2-(2-naphthal...)
Affinity DataKi:  6.10E+3nMAssay Description:The compound was evaluated for inhibition of cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed