BDBM50113489 CHEMBL3604621

SMILES CC(=O)Nc1nc2ccc(cc2s1)-c1cnc(Cl)c(NC(C#N)c2ccccc2)c1

InChI Key InChIKey=RUGCYCMPTFYHPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113489   

LigandPNGBDBM50113489(CHEMBL3604621)
Affinity DataIC50:  490nMAssay Description:Inhibition of PI3Kalpha (unknown origin) assessed as reduction in luminescence signaling by kinase-Glo plus luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mouse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50113489(CHEMBL3604621)
Affinity DataIC50:  100nMAssay Description:Inhibition of SMO in mouse NIH/3T3 cells assessed as inhibition of SAG-induced hedgehog-mediated luminescence signaling by GRE-luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed