BDBM50115108 (5-bromopyridin-2-ylamino)methylenediphosphonic acid::CHEMBL100483::[(5-Bromo-pyridin-2-ylamino)-phosphono-methyl]-phosphonic acid::[[(5-bromo-2-pyridinyl)amino]methylene]-1,1-bisphosphonate

SMILES OP(O)(=O)C(Nc1ccc(Br)cn1)P(O)(O)=O

InChI Key InChIKey=QMTRPEYMFKONLX-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115108   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50115108((5-bromopyridin-2-ylamino)methylenediphosphonic ac...)
Affinity DataKi:  140nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50115108((5-bromopyridin-2-ylamino)methylenediphosphonic ac...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50115108((5-bromopyridin-2-ylamino)methylenediphosphonic ac...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed