BDBM50115136 2-Amino-5-benzoyl-5,6,7,8-tetrahydro-3H-pteridin-4-one::CHEMBL101495

SMILES Nc1nc2NCCN(C(=O)c3ccccc3)c2c(=O)[nH]1

InChI Key InChIKey=CEVLENUPGOKMCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115136   

TargetNitric oxide synthase, brain(Human)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115136(2-Amino-5-benzoyl-5,6,7,8-tetrahydro-3H-pteridin-4...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115136(2-Amino-5-benzoyl-5,6,7,8-tetrahydro-3H-pteridin-4...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115136(2-Amino-5-benzoyl-5,6,7,8-tetrahydro-3H-pteridin-4...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115136(2-Amino-5-benzoyl-5,6,7,8-tetrahydro-3H-pteridin-4...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed