BDBM50115154 2-Amino-6-(4-fluoro-phenyl)-3H-pteridin-4-one::CHEMBL98102

SMILES Nc1nc2ncc(nc2c(=O)[nH]1)-c1ccc(F)cc1

InChI Key InChIKey=OAPKFNQPDNASHY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115154   

TargetNitric oxide synthase, brain(Human)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115154(2-Amino-6-(4-fluoro-phenyl)-3H-pteridin-4-one | CH...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, inducible(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115154(2-Amino-6-(4-fluoro-phenyl)-3H-pteridin-4-one | CH...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, endothelial(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115154(2-Amino-6-(4-fluoro-phenyl)-3H-pteridin-4-one | CH...)
Affinity DataIC50:  2.53E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, brain(Human)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115154(2-Amino-6-(4-fluoro-phenyl)-3H-pteridin-4-one | CH...)
Affinity DataIC50:  6.55E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed