BDBM50115155 7-Amino-3,3a,4,5-tetrahydro-8H-2-oxa-5,6,8,9b-tetraaza-cyclopenta[a]naphthalene-1,9-dione::CHEMBL101885

SMILES Nc1nc2NCC3COC(=O)N3c2c(=O)[nH]1

InChI Key InChIKey=XAZOBOCYEGBXHD-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115155   

TargetNitric oxide synthase, brain(Human)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115155(7-Amino-3,3a,4,5-tetrahydro-8H-2-oxa-5,6,8,9b-tetr...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, brain(Human)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115155(7-Amino-3,3a,4,5-tetrahydro-8H-2-oxa-5,6,8,9b-tetr...)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, endothelial(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115155(7-Amino-3,3a,4,5-tetrahydro-8H-2-oxa-5,6,8,9b-tetr...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetNitric oxide synthase, inducible(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115155(7-Amino-3,3a,4,5-tetrahydro-8H-2-oxa-5,6,8,9b-tetr...)
Affinity DataIC50:  3.74E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed