BDBM50115643 (+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,4a-diaza-tribenzo[a,c,e]cycloheptene::CHEMBL324270

SMILES COc1cccc2Cc3ccccc3C3CN(C)CCN3c12

InChI Key InChIKey=GZXNMNCAWGIAAW-UHFFFAOYSA-N

Data  7 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50115643   

Target5-hydroxytryptamine receptor 2C(Rat)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  0.210nMAssay Description:The binding affinity at 5-hydroxytryptamine 2C receptor was determined using [3H]mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  0.700nMAssay Description:The binding affinity at 5-hydroxytryptamine 2A receptor was determined using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  28nMAssay Description:The binding affinity at the Dopamine receptor D2 determined using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  92nMAssay Description:The binding affinity at the Dopamine receptor D4 determined using [3H]YM-09151-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  260nMAssay Description:The binding affinity at the Dopamine receptor D3 determined using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  345nMAssay Description:The binding affinity at the 5-hydroxytryptamine 1A receptor determined using [3H]5-CTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataIC50: 1.78E+3nMAssay Description:The binding affinity at the Norepinephrine transporter reuptake sites determined using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataIC50: 2.90E+3nMAssay Description:The binding affinity at the 5-HT reuptake sites determined using competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  2.90E+3nMAssay Description:The binding affinity at 5-hydroxytryptamine 3 receptor was determined using [3H]LY-278584More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed