BDBM50115866 6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexyloxy)-phenyl]-1H-benzoimidazole-5-carboxamidine::CHEMBL294067

SMILES C[C@H]1CCC[C@H](Oc2cccc(-c3nc4cc(F)c(C(=N)N)cc4[nH]3)c2O)C1

InChI Key InChIKey=AJFFZXMHLLIFML-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115866   

TargetUrokinase-type plasminogen activator(Human)
Celera

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115866BDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  180nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Celera

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115866BDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Celera

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115866BDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115866BDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Celera

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115866BDBM50115866(6-Fluoro-2-[2-hydroxy-3-((S)-3-methyl-cyclohexylox...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed