BDBM50115929 4-[3-(4-Cyano-benzyl)-2-methyl-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid benzyl ester::CHEMBL64168

SMILES Cc1ncc(CN2CCN(CC2)C(=O)OCc2ccccc2)n1Cc1ccc(cc1)C#N

InChI Key InChIKey=FBTSVHIGWRLBOS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115929   

LigandPNGBDBM50115929(4-[3-(4-Cyano-benzyl)-2-methyl-3H-imidazol-4-ylmet...)
Affinity DataIC50: 19nMAssay Description:Inhibitor of Farnesyl protein transferase (FTPase) required to reduce radiolabel [1-3H] incorporation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50115929(4-[3-(4-Cyano-benzyl)-2-methyl-3H-imidazol-4-ylmet...)
Affinity DataIC50: 789nMAssay Description:Inhibition of [1-3H]-GGPP incorporation into biotinylated K4B-Ras peptide by geranylgeranyl transferase in the presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed