BDBM50116621 3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicyclo[3.3.1]non-5-yl]-phenol::CHEMBL333342

SMILES CC1CN(CCCc2ccccc2)C2C[C@H](N)CC1(C2)c1cccc(O)c1

InChI Key InChIKey=DBPFGWTUHBQYTM-LGZXGLGHSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50116621   

TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataKi:  3.30nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataKi:  14.7nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataKi:  122nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataKi:  207nMAssay Description:Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataKi:  246nMAssay Description:Ability to displace [3H]DADLE from Opioid receptor delta 1 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataKi:  893nMAssay Description:Ability to displace [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataEC50:  1.95E+4nMAssay Description:Agonist activity at human cloned mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50116621(3-[7-Amino-4-methyl-2-(3-phenyl-propyl)-2-aza-bicy...)
Affinity DataEC50:  7.50E+3nMAssay Description:Agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed