BDBM50116926 (S)-4-(1-Furo[3,2-c]pyridin-2-yl-1-methyl-ethyl)-1-[(2S,4R)-2-hydroxy-4-((3S,4S)-3-hydroxy-chroman-4-ylcarbamoyl)-5-phenyl-pentyl]-piperazine-2-carboxylic acid cyclopentylamide::CHEMBL82245

SMILES CC(C)(N1CCN(C[C@@H](O)C[C@@H](Cc2ccccc2)C(=O)N[C@@H]2[C@H](O)COc3ccccc23)[C@@H](C1)C(=O)NC1CCCC1)c1cc2cnccc2o1

InChI Key InChIKey=YCWHOUFNTCROPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116926   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116926((S)-4-(1-Furo[3,2-c]pyridin-2-yl-1-methyl-ethyl)-1...)
Affinity DataIC50: 0.370nMAssay Description:Inhibitory concentration required to inhibit cleavage of a substrate by thewild-type HIV-1 protease enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed