BDBM50118173 CHEMBL3613003

SMILES COc1nn(Cc2cccc(N)c2)c(=O)o1

InChI Key InChIKey=QGFPZGVBASJTKW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50118173   

TargetMonoacylglycerol lipase ABHD6(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118173(CHEMBL3613003)
Affinity DataIC50:  3.63E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118173(CHEMBL3613003)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118173(CHEMBL3613003)
Affinity DataIC50:  219nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118173(CHEMBL3613003)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118173(CHEMBL3613003)
Affinity DataIC50:  216nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50118173(CHEMBL3613003)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed