BDBM50118180 CHEMBL3613167

SMILES [H][C@]12C[C@@]34Cc5ccc(O)cc5[C@@]3(CCN(CC3CC3)[C@@]4([H])C=C1)C[C@@H]2N(C)C(=O)C=Cc1ccoc1

InChI Key InChIKey=ZIHVJXZITLDMSJ-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118180   

TargetKappa-type opioid receptor(Mouse)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50118180(CHEMBL3613167)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50118180(CHEMBL3613167)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50118180(CHEMBL3613167)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DPDPE from DOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50118180(CHEMBL3613167)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed