BDBM50118415 CHEMBL3612664
SMILES CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(F)c23)c1
InChI Key InChIKey=BROIYLJWUMQYQV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50118415
Affinity DataIC50: 126nMAssay Description:Displacement of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of full-length His6-tagged BRAF V600E mutant (2 to 766 residues) (unknown origin) expressed in baculovirus system by B-Raf accelerated MEK...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Displacement of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of His6-tagged full length BRAF V600E mutant (2 to 766 residues) (unknown origin) expressed in Baculovirus expression system by BRAMA meth...More data for this Ligand-Target Pair