BDBM50118598 4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-phenyl-allyl)-piperidine::CHEMBL137718

SMILES Fc1ccc(cc1)C(OCCC1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=XCEOQSGAJFHDBK-QPJJXVBHSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118598   

TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118598(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118598(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  47nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50118598(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against dopamine transporter (DAT) labeled with [3H]-WIN- 35,428 in rat brain striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118598(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataIC50:  271nMAssay Description:Inhibitory activity against serotonin transporter (SERT) labeled with [3H]-citalopram in rat brain striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed