BDBM50118599 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphthalen-2-ylmethyl)piperidine::4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-naphthalen-2-ylmethyl-piperidine::CHEMBL416409

SMILES Fc1ccc(cc1)C(OCCC1CCN(Cc2ccc3ccccc3c2)CC1)c1ccc(F)cc1

InChI Key InChIKey=GGGXMDDQIHPMRC-UHFFFAOYSA-N

Data  9 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50118599   

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  0.700nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  0.710nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [125I]RTI55 from DAT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  88nMAssay Description:Affinity at rat serotonin transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  93nMAssay Description:Inhibition of [3H]-norepinephrine uptake at the rat norepinephrine transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  227nMAssay Description:Inhibition of [3H]-5-HT uptake at the rat serotonin transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  229nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  229nMAssay Description:Displacement of [125I]RTI55 from SERT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataIC50:  93nMAssay Description:Compound was tested for the inhibition of norepinephrine (NE) reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataIC50:  7.20nMAssay Description:Compound was tested for the inhibition of dopamine (DA) reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataIC50:  277nMAssay Description:Compound was tested for the inhibition of serotonin (5-HT) reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed