BDBM50118810 (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenylpropan-2-ylamino)-9H-purin-9-yl)-tetrahydrofuran-3,4-diol::2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol::CHEMBL139000::N6-[(R)-1-Methyl-2-phenylethyl]ado (R-PIA)::R-N6-(phenylisopropyl)adenosine
SMILES C[C@H](Cc1ccccc1)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
InChI Key InChIKey=RIRGCFBBHQEQQH-SSFGXONLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 60 hits for monomerid = 50118810
Affinity DataKi: 0.25nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to bovine brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of [3H]CHA (N6-cyclohexyl adenosine) to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Antagonist binding of 2-chloro-[3H]-adenosine to rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity against high affinity component of adenosine A1 receptors from rat brain membranes using [3H]DPCPXMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding affinity for adenosine A1 receptor in rat brain membranes using [3H]CHA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity towards adenosine A1 receptor on rat whole brain membrane using [3H]N6-cyclohexyladenosineMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]CHA from adenosine A1 receptor of rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to adenosine A1 receptor in rat whole brain membranes by [3H]N6-cyclohexyladenosine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of [3H]- (R)-P1A binding to adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity for Adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]-CHAMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity at adenosine A1 receptor from rat brain membranes by [3H]N6-cyclohexyladenosine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to rat testesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to rat brainMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]CPPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Evaluated for the binding affinity towards the Adenosine A1 receptor in corpora striata of rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Intrinsic activity towards Adenosine A1 receptor as displacement of [3H]DPCPX from bovine cortical membranes without GTPMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat fatMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Affinity for human Adenosine A3 receptor expressed in CHO cellMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Affinity for the Adenosine A1 receptor in the absence of GTP (A1-GTP) by using [3H]DPCPX as radioligandMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Binding affinity to adenosine A3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 19.9nMAssay Description:Intrinsic activity towards Adenosine A1 receptor as displacement of [3H]DPCPX from bovine cortical membranes with 1 mM GTPMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H](R)-PIA binding to rat testis membranesMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Affinity to Adenosine A3 receptor of rat testis membrane using [3H](R)-PIA with 150 nM DPCPXMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Affinity for the Adenosine A1 receptor in the presence of GTP (A1+GTP) by using [3H]-DPCPX as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Binding affinity for adenosine A2 receptor in rat striatal membranes using [3H]NECA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Binding affinity towards adenosine A2 receptor on rat striatal membrane using [3H]NECA as radioligandMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Affinity DataKi: 124nMAssay Description:Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 124nMAssay Description:Binding affinity at adenosine A2 receptor from rat striatal membranes by [3H]NECA displacement.More data for this Ligand-Target Pair
Affinity DataKi: 124nMAssay Description:Binding affinity to A2 adenosine receptor in rat striatal membranes by [3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide)...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Affinity DataKi: 140nMAssay Description:Binding affinity against Adenosine A2A receptor by using [3H]CGS-21680 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity against low affinity component of adenosine A1 receptors from rat brain membranes using [3H]-DPCPXMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity against low affinity component of adenosine A1 receptors from rat brain membranes using [3H]-DPCPXMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of [3H]- NECA binding to adenosine receptor A2More data for this Ligand-Target Pair
Affinity DataKi: 730nMAssay Description:Binding affinity against adenosine A2 receptor from rat striatal membranes with 50 nM CPA using [3H]-NECAMore data for this Ligand-Target Pair
Affinity DataKi: 730nMAssay Description:Displacement of [3H]NECA from A2-receptor of rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes.More data for this Ligand-Target Pair
Affinity DataKi: 884nMAssay Description:Displacement of [3H]CGS-21680 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Binding affinity against adenosine A1 receptors from rat brain membranes using [3H]CCPAMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMAssay Description:Binding affinity for Adenosine A2 receptor in corpora striata of rats using [3H]NECAMore data for this Ligand-Target Pair
Affinity DataEC50: 950nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair