BDBM50119735 3-Cyano-N-{(S)-1-[3-(4-cyclopropanecarbonyl-phenoxy)-propyl]-pyrrolidin-3-yl}-benzenesulfonamide::CHEMBL101748

SMILES O=C(C1CC1)c1ccc(OCCCN2CC[C@@H](C2)NS(=O)(=O)c2cccc(c2)C#N)cc1

InChI Key InChIKey=ICDXLEXUWOLRPG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119735   

TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119735(3-Cyano-N-{(S)-1-[3-(4-cyclopropanecarbonyl-phenox...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity towards rats Histamine type 3 (H3) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119735(3-Cyano-N-{(S)-1-[3-(4-cyclopropanecarbonyl-phenox...)
Affinity DataKi:  900nMAssay Description:Binding affinity towards human Histamine H2 receptor (For compound 11)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50119735(3-Cyano-N-{(S)-1-[3-(4-cyclopropanecarbonyl-phenox...)
Affinity DataKi:  8.90E+3nMAssay Description:Binding affinity to the human Histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed