BDBM50119811 1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]phenyl}-2-chlorobenzamide::CHEMBL318392

SMILES Clc1ccc2N(C[C@@H]3C4CCC(CC4)N3Cc2c1)C(=O)c1ccc(NC(=O)c2ccccc2Cl)cc1

InChI Key InChIKey=UFARQGNCEDRJRW-IBYOELKQSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50119811   

TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50119811(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataKi:  520nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50119811(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataKi:  620nMAssay Description:Inhibition of [3H]-Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V2 receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50119811(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]-Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V1a receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50119811(1N-{4-[6-chloro-16-ethyl-(12S)-2,10-diazatetracycl...)
Affinity DataIC50:  35nMAssay Description:Inhibition of [3H]-Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed