BDBM50119879 (S)-N-((4S,6S,7S)-7-(2-(2,6-dimethylphenoxy)acetamido)-6-hydroxy-2-methyl-8-phenyloctan-4-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide::CHEMBL104538::N-{4-[2-(2,6-Dimethyl-phenoxy)-acetylamino]-3-hydroxy-1-isobutyl-5-phenyl-pentyl}-3-methyl-2-(2-oxo-tetrahydro-pyrimidin-1-yl)-butyramide

SMILES CC(C)C[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)COc1c(C)cccc1C)NC(=O)[C@H](C(C)C)N1CCCNC1=O

InChI Key InChIKey=GHRJLZLPJSUIDV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119879   

TargetProtease(Human immunodeficiency virus type 1)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50119879(N-{4-[2-(2,6-Dimethyl-phenoxy)-acetylamino]-3-hydr...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of HIV-1 NL4-3 wild type protease expressed in Escherichia coli preincubated for 20 mins by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50119879(N-{4-[2-(2,6-Dimethyl-phenoxy)-acetylamino]-3-hydr...)
Affinity DataKi:  357nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed