BDBM50120466 CHEMBL3617986

SMILES CC(C)OC(=O)C(Cn1ccnc1)NC(=O)c1c(C)nn(c1Cl)-c1ccccc1

InChI Key InChIKey=CVZOIBZVGKOLJA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120466   

TargetCytochrome P450 26A1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120466(CHEMBL3617986)
Affinity DataIC50: 460nMAssay Description:Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120466(CHEMBL3617986)
Affinity DataIC50: 4.92E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) incubated for 45 mins using NADPH by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50120466(CHEMBL3617986)
Affinity DataIC50: 9.64E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) incubated for 45 mins using NADPH and ATRA by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed