BDBM50121369 CHEMBL3621215

SMILES Cc1ccccc1N1CCOc2cnc(NC3CCN(CC3)c3ccnc(Cl)c3)nc12

InChI Key InChIKey=YZZHGHAMABZSAP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121369   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Temple University

Curated by ChEMBL

LigandBDBM50121369(CHEMBL3621215)Copy SMILESCopy InChI

Affinity DataIC50: 90nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing human wild type APP75I cDNA assessed as reduction in amyloid beta peptides incubated for 1...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/4/2016
Entry Details Article
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