BDBM50121885 (S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::Bu-His-DPhe-Arg-Trp-Gly-NH2::CHEMBL29582

SMILES CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O

InChI Key InChIKey=LVACOVVOTCZAIW-UHFFFAOYSA-N

Data  8 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50121885   Sort by

TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  10nMAssay Description:Agonist activity against human melanocortin receptor hMC1R at 50% maximum cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity towards human melanocortin receptor hMC3R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  20nMAssay Description:Effective concentration for cAMP accumulation mediated by human Melanocortin 4 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 580nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity towards human Melanocortin 5 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  10nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  20nMAssay Description:Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  10nMAssay Description:Agonist activity in HEK293 cells transfected with human MC1R by cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 1.33E+4nMAssay Description:Binding affinity towards human melanocortin receptor hMC5R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  20nMAssay Description:Agonist activity against human melanocortin receptor hMC4RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 580nMAssay Description:Binding affinity towards human melanocortin receptor hMC1R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  10nMAssay Description:Agonist activity against human melanocortin receptor hMC1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human melanocortin receptor hMC4R by using radioligand NDP-MSHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed