BDBM50122305 CHEMBL552629::N-(3-{[3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-propylamino]-methyl}-phenyl)-thiophene-2-carboxamidine; hydrochloride

SMILES CC(C)(C)c1cc(CCCNCc2cccc(c2)N=C(N)c2cccs2)cc(c1O)C(C)(C)C

InChI Key InChIKey=YNXPHJZTYZMLFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122305   

TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50122305(CHEMBL552629 | N-(3-{[3-(3,5-Di-tert-butyl-4-hydro...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50122305(CHEMBL552629 | N-(3-{[3-(3,5-Di-tert-butyl-4-hydro...)
Affinity DataIC50:  470nMAssay Description:Inhibitory concentration tested against neuronal nitric oxide synthase (nNOS ) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed