BDBM50122319 CHEMBL3622150

SMILES CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3cc(C)[nH]n3)nc21

InChI Key InChIKey=QBMBKEGWVSJZNL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122319   

TargetTyrosine-protein kinase JAK2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122319BDBM50122319(CHEMBL3622150)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) using 5-FAM-KKKKEEIYFFFG-OH substrate and ATP incubated for 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2016
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122319BDBM50122319(CHEMBL3622150)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant TYK2 (unknown origin) by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122319BDBM50122319(CHEMBL3622150)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using 5-FAM-KKKKEEIYFFFG-OH substrate and ATP incubated for 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122319BDBM50122319(CHEMBL3622150)
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using 5-FAM-KKKKEEIYFFFG-OH substrate and ATP incubated for 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2016
Entry Details Article
PubMed