BDBM50122340 (S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-propionic acid::CHEMBL314483

SMILES [#6]-[#6]-[#8]-[#6@@H](-[#6]-c1ccc(-[#8]-[#6]\[#6]=[#6](/c2ccccc2)-c2ccccc2)cc1)-[#6](-[#8])=O

InChI Key InChIKey=VIZRKWWMIFWRJH-VWLOTQADSA-N

Data  3 Kd  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50122340   

LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  6.40E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  2.70E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  2.70E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  6.40E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor delta(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  5.70E+3nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor delta (PPAR delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  6.46E+3nMAssay Description:Transactivation of Homo sapiens (human) PPARalpha assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  6.40E+3nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity towards peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataKd:  6.40E+3nMAssay Description:Binding affinity towards peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataKd:  5.70E+3nMAssay Description:Binding affinity towards peroxisome proliferator activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  2.69E+3nMAssay Description:Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122340((S)-3-[4-(3,3-Diphenyl-allyloxy)-phenyl]-2-ethoxy-...)
Affinity DataEC50:  2.70E+3nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed