BDBM50122989 3-Benzo[1,3]dioxol-5-yl-2-[5-(3-trifluoromethyl-phenyl)-furan-2-carbonyl]-1,2,3,4-tetrahydro-pyrrolo[3,4-b]quinolin-9-one::CHEMBL344152

SMILES Oc1c2CN(C(c2nc2ccccc12)c1ccc2OCOc2c1)C(=O)c1ccc(o1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=DTVQHOVWOLPNJL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122989   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50122989(3-Benzo[1,3]dioxol-5-yl-2-[5-(3-trifluoromethyl-ph...)
Affinity DataKi:  0.980nMAssay Description:Inhibitory activity against Phosphodiesterase 5 (PDE5) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed