BDBM50123002 2-Benzyl-7-(4-fluoro-phenyl)-8-pyridin-4-yl-3,6-dihydro-imidazo[4,5-e]indole::2-benzyl-7-(4-fluorophenyl)-8-(pyridin-4-yl)-3,6-dihydroimidazo[4,5-e]indole::CHEMBL331215

SMILES Fc1ccc(cc1)-c1[nH]c2ccc3[nH]c(Cc4ccccc4)nc3c2c1-c1ccncc1

InChI Key InChIKey=ZGXVMEYUYQMAQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123002   

TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50123002(2-Benzyl-7-(4-fluoro-phenyl)-8-pyridin-4-yl-3,6-di...)
Affinity DataIC50:  60nMAssay Description:Inhibition of LPS-induced p38-related TNF-alpha production in human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50123002(2-Benzyl-7-(4-fluoro-phenyl)-8-pyridin-4-yl-3,6-di...)
Affinity DataIC50:  22nMAssay Description:Inhibition of murine p38 alpha kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed