BDBM50123190 CHEMBL3622645::US9388170, 13

SMILES CN(C)C\C=C\C(=O)Nc1cc2c(Nc3cccc(c3)C#C)ncnc2cc1O[C@H]1CCOC1

InChI Key InChIKey=XOLQJGVNGIZVGW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123190   

TargetEpidermal growth factor receptor(Human)
Qilu Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50123190(CHEMBL3622645 | US9388170, 13)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EGFR (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50123190(CHEMBL3622645 | US9388170, 13)
Affinity DataIC50: 57nMAssay Description:BT474 Cell Line: 1. 5×103 cells per well in 100 μl of medium were seeded in 96-well plate, here the medium contained 5% FBS2. 24 hours later, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
US Patent

LigandPNGBDBM50123190(CHEMBL3622645 | US9388170, 13)
Affinity DataIC50: 100nMAssay Description:BT474 Cell Line: 1. 5×103 cells per well in 100 μl of medium were seeded in 96-well plate, here the medium contained 5% FBS2. 24 hours later, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
US Patent

LigandPNGBDBM50123190(CHEMBL3622645 | US9388170, 13)
Affinity DataIC50: 3.10E+3nMAssay Description:A431 Cell Line: 1. 5×103 cells per well in 100 μl of medium were seeded in 96-well plate, here the medium contained 5% FBS2. 24 hours later, 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
US Patent