BDBM50123249 (S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phenyl)-thiophene-2-carbonyl]-amino}-propionic acid; TFA::CHEMBL344535

SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(c1)-c1ccc(s1)-[#6](=O)-[#7]-[#6]-[#6@H](-[#7]S(=O)(=O)c1ccccc1)-[#6](-[#8])=O

InChI Key InChIKey=XGMBDTKPGSGTQW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50123249   

TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 1nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of vitronectin binding to HT-29 cells expressing integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 95nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alpha5-beta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed