BDBM50123250 (S)-2-Benzenesulfonylamino-3-{[5-(4-guanidinomethyl-phenyl)-thiophene-2-carbonyl]-amino}-propionic acid; TFA::CHEMBL148147

SMILES NC(=N)NCc1ccc(cc1)-c1ccc(s1)C(=O)NC[C@H](NS(=O)(=O)c1ccccc1)C(O)=O

InChI Key InChIKey=VJJPPEQXMGSWDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123250   

TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123250((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidinomethy...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123250((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidinomethy...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123250((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidinomethy...)
Affinity DataIC50: 730nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed