BDBM50123490 CHEMBL143418::N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-[3-(2,2-difluoro-2-pyridin-2-yl-ethylamino)-6-methyl-2-oxo-2H-pyrazin-1-yl]-acetamide

SMILES Cc1cnc(NCC(F)(F)c2ccccn2)c(=O)n1CC(=O)NCc1ccc(N)nc1C

InChI Key InChIKey=OWCMVQFLPIOYNL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50123490   

TargetProthrombin(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50123490(CHEMBL143418 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  0.0420nMAssay Description:Inhibition of Thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50123490(CHEMBL143418 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  0.0420nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50123490(CHEMBL143418 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  0.0420nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTrypsin(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50123490(CHEMBL143418 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  800nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123490(CHEMBL143418 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)
Affinity DataKi:  800nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed