BDBM50123668 CHEMBL3622734

SMILES CCCC(=O)c1c([nH]c2cc(Cl)ccc12)C(=O)OCC

InChI Key InChIKey=FFIVDIXESPKPHB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123668   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123668(CHEMBL3622734)
Affinity DataKi:  290nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50123668(CHEMBL3622734)
Affinity DataIC50: 730nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed