BDBM50124002 8-Amino-3-cyclopropylmethyl-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL422560

SMILES C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(N)ccc1C2=O

InChI Key InChIKey=NVNLCWUDSURWQS-GQWBRKQSSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124002   

TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50124002(8-Amino-3-cyclopropylmethyl-6,11-dimethyl-3,4,5,6-...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards Opioid receptor kappa 1 from guinea pig brain using [3H]U69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50124002(8-Amino-3-cyclopropylmethyl-6,11-dimethyl-3,4,5,6-...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity towards Opioid receptor mu 1 from guinea pig brain using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50124002(8-Amino-3-cyclopropylmethyl-6,11-dimethyl-3,4,5,6-...)
Affinity DataKi:  29nMAssay Description:Binding affinity towards Opioid receptor delta 1 from guinea pig brain using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50124002(8-Amino-3-cyclopropylmethyl-6,11-dimethyl-3,4,5,6-...)
Affinity DataEC50:  180nMAssay Description:Incorporation of [35S]- GTPgammaS into CHO membranes expressing human Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50124002(8-Amino-3-cyclopropylmethyl-6,11-dimethyl-3,4,5,6-...)
Affinity DataEC50:  9.70nMAssay Description:Incorporation of [35S]GTP-gamma-S, into CHO membranes expressing human Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed