BDBM50124067 4-((R)-3-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-benzylamino)-6-[(R)-1-((S)-6,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0*2,6*]dec-4-yl)-propylcarbamoyl]-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidin-8-yl}-ureido)-benzoic acid ethyl ester::CHEMBL354990

SMILES CCOC(=O)c1ccc(NC(=O)N[C@]2(C)C[C@@H](C(=O)N[C@@H](CC)B3OC4C5CC(C[C@]4(C)O3)C5(C)C)n3c2ncc(NCc2cccc(c2)C(F)(F)F)c3=O)cc1

InChI Key InChIKey=HBBHABDTVWCOFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124067   

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124067(4-((R)-3-{(S)-8-Methyl-4-oxo-3-(3-trifluoromethyl-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity hepatitis C virus NS3 protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed