BDBM50124191 (S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine::CHEMBL353220

SMILES COc1ccc(Br)cc1C1=N[C@H](CN2CCN(CC2)c2ccccc2)CCN1

InChI Key InChIKey=RVBVZFLMCDGFOZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124191   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124191((S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piper...)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D3 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124191((S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piper...)
Affinity DataKi:  3.50E+3nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D4 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124191((S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piper...)
Affinity DataKi:  9.10E+3nMAssay Description:In vitro Binding affinity towards dopamine D1 receptor using bovine striatal membrane preparations and antagonist [3H]-SCH- 23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124191((S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piper...)
Affinity DataKi:  1.60E+4nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D2 long in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124191((S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piper...)
Affinity DataKi:  1.60E+4nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D2 long in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed