BDBM50124196 (S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6-dihydro-3H-pyrimidin-4-one::CHEMBL168541

SMILES O=C1C[C@@H](CN2CCN(CC2)c2ccccc2)NC(=N1)c1ccccc1

InChI Key InChIKey=DKXYPAWNMBQJBN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124196   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124196((S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6...)
Affinity DataKi:  3.70E+3nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D4 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124196((S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6...)
Affinity DataKi:  6.40E+3nMAssay Description:In vitro binding affinity to displace [3H]-spiperone from the cloned human dopamine receptor D2 short in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124196((S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6...)
Affinity DataKi:  8.90E+3nMAssay Description:In vitro Binding affinity towards dopamine D1 receptor using bovine striatal membrane preparations and antagonist [3H]-SCH- 23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124196((S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6...)
Affinity DataKi:  1.80E+4nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D2 long in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50124196((S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6...)
Affinity DataKi:  2.00E+4nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D3 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed