BDBM50124231 2-{[1-((S)-Ethanesulfonyl)-cyclopentanecarbonyl]-amino}-3-(2'-methoxy-biphenyl-4-yl)-propionic acid::CHEMBL171929

SMILES CCS(=O)(=O)C1(CCCC1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1OC)C(O)=O

InChI Key InChIKey=HWTDZVDHOSKTML-FQEVSTJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124231   

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124231(2-{[1-((S)-Ethanesulfonyl)-cyclopentanecarbonyl]-a...)
Affinity DataIC50:  58nMAssay Description:Binding affinity towards VLA-4 (alpha4 beta-1) receptor in human Jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124231(2-{[1-((S)-Ethanesulfonyl)-cyclopentanecarbonyl]-a...)
Affinity DataIC50:  0.530nMAssay Description:Binding affinity towards VLA-4 (alpha4 beta-1) receptor in human Jurkat cells using [125I]VCAM-Ig as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed